This fluorescence in situ hybridization (FISH) image is of human chromosomes from a single cell: the chromosomes are stained in blue and a DNA probe for the GLI1 gene (located on chromosome 12 at band q13) is stained in red. The significance of this photo is not in the implicit science, but that, although I didn’t do the phlebotomy (!), I independently cultured the source blood, prepared the metaphase chromosomes for analysis, determined the appropriate primers for probe synthesis and labelled the probe, did the FISH preparation, and took and printed the images. I also set up the system for light and fluorescence microscopy to capture the images. This work was done as a staff scientist in the McDougall lab at the Fred Hutchinson Cancer Research Center in Seattle.